Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Do Cobalt-Chromium Femoral Heads Have Reduced Revision Risk Compared to Stainless Steel Metal Heads With a Single Cemented Femoral Design? A New Zealand Joint Registry Study.

The Journal of arthroplasty·2026
Same author

Letter to the Editor: Editor's Spotlight/Take 5: CORR Synthesis: What Is the Role of Robotic-assisted Technology in Knee Arthroplasty?

Clinical orthopaedics and related research·2026
Same author

Have we come to the end of the patient-reported outcome measure (PROM)? : wearable sensors highlight improved rate of recovery and range of motion following robotic-assisted total knee arthroplasty that are overlooked by conventional PROMs.

The bone & joint journal·2026
Same author

High glucose upregulates BMAL1 in chondrocytes from macroscopically normal and osteoarthritic human cartilage but this only results in increased collagen synthesis in chondrocytes from macroscopically normal cartilage regions.

Osteoarthritis and cartilage open·2026
Same author

Preliminary cadaver study of Surgical Humidification (HumiGard™) demonstrating reduced intra-wound particle counts during total hip arthroplasty.

The Journal of hospital infection·2025
Same author

CORR Insights®: High Risk of Venous Thromboembolism With Aspirin Prophylaxis After THA for High-riding Developmental Dysplasia of the Hip: A Retrospective, Comparative Study.

Clinical orthopaedics and related research·2025

Related Experiment Video

Updated: Jun 6, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
10:35

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

Infection in total hip replacement: meta-analysis.

Surendra Senthi1, Jacob T Munro, Rocco P Pitto

  • 1Department of Orthopaedic Surgery, Middlemore Hospital, South Auckland Clinical School, University of Auckland, Private Bag, 93311, Auckland, New Zealand.

International Orthopaedics
|November 19, 2010
PubMed
Summary

Managing deep infections after total hip arthroplasty (THA) is challenging. Recent literature reviews explore implant retention and one-stage revision strategies, alongside concerns about antibiotic resistance.

More Related Videos

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials
06:18

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials

Published on: March 3, 2023

A Periprosthetic Joint Candida albicans Infection Model in Mouse
04:37

A Periprosthetic Joint Candida albicans Infection Model in Mouse

Published on: February 2, 2024

Related Experiment Videos

Last Updated: Jun 6, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
10:35

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials
06:18

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials

Published on: March 3, 2023

A Periprosthetic Joint Candida albicans Infection Model in Mouse
04:37

A Periprosthetic Joint Candida albicans Infection Model in Mouse

Published on: February 2, 2024

Area of Science:

  • Orthopedic Surgery
  • Infectious Diseases
  • Biomedical Engineering

Background:

  • Deep infection is a significant complication following total hip arthroplasty (THA), a highly successful surgical procedure.
  • Managing these infections is complex and requires careful consideration of treatment strategies.
  • Recent advancements and evolving challenges necessitate a review of current management practices.

Purpose of the Study:

  • To review the latest literature on managing deep infections in total hip arthroplasty.
  • To focus on clinically relevant articles published within the last five years.
  • To synthesize current evidence on revision strategies and antibiotic use.

Main Methods:

  • Comprehensive literature search using MEDLINE, PubMed, and Cochrane database.
  • Inclusion of clinically relevant articles published in the last five years.
  • Cross-checking of references from selected articles.

Main Results:

  • Two-stage revision remains a gold standard, but implant retention and one-stage revision strategies show promising outcomes.
  • Complex reconstruction options are effective for patients with severe bone stock loss.
  • Controversy exists regarding optimal antibiotic therapy duration, with concerns about rising bacterial resistance.

Conclusions:

  • While two-stage revision is standard, emerging evidence supports alternative strategies like implant retention and one-stage revisions.
  • Effective management of bone stock loss is crucial in complex cases.
  • Careful antibiotic selection and stewardship are vital due to increasing bacterial resistance.