Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Kidney Transplant II: Surgical Procedure

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

Kidney Transplant III: Nursing Management

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...

Kidney Transplant I: Introduction

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

Imaging Studies V: Intravenous Urography and Retrograde Pyelography

Imaging Studies V: Intravenous Urography and Retrograde Pyelography

IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...

Urinary Tract Calculi VI: Surgical Management

Urinary Tract Calculi VI: Surgical Management

Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...

Imaging Studies I: Kidney, Ureter, and Bladder Studies

Imaging Studies I: Kidney, Ureter, and Bladder Studies

Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The impact of the CB2-63 polymorphism on the histological presentation of chronic hepatitis B.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2015

Same author

Factors influencing liver fibrosis and necroinflammation in HIV/HCV coinfection and HCV monoinfection.

Infection·2013

Same author

Tolerability and efficacy of anti-HBV nucleos(t)ide analogues in HBV-DNA-positive cirrhotic patients with HBV/HCV dual infection.

Journal of viral hepatitis·2012

Same author

[Prostate cancer: transrectal high-intensity focused ultrasound for the treatment of local recurrence after radical prostatectomy or radiotherapy].

Urologia·2010

Same author

[Penile prosthesis implantation in kidney-transplanted patients].

Urologia·2010

Same author

Value of endorectal MRI and MRS in patients with elevated prostate-specific antigen levels and previous negative biopsies to localize peripheral zone tumours.

Clinical radiology·2008

Search research articles

Related Experiment Video

Updated: Jun 6, 2026

A Modified Surgical Technique for Kidney Transplantation in Mice

A Modified Surgical Technique for Kidney Transplantation in Mice

Published on: July 22, 2022

[Bladder augmentation and urinary diversions in kidney transplants].

F Lasaponara, G Pasquale, G Cucchiarale

|November 19, 2010

Summary

Kidney transplants in patients with augmented bladders are feasible using porcine small intestinal submucosa (SIS). This biomaterial creates a compliant reservoir, potentially reducing complications and improving graft survival in high-risk recipients.

More Related Videos

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Published on: August 9, 2012

Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs

Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs

Published on: July 5, 2024

Related Experiment Videos

Last Updated: Jun 6, 2026

A Modified Surgical Technique for Kidney Transplantation in Mice

A Modified Surgical Technique for Kidney Transplantation in Mice

Published on: July 22, 2022

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Published on: August 9, 2012

Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs

Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs

Published on: July 5, 2024

Area of Science:

Biomaterials Science
Urology
Transplantation Surgery

Context:

Kidney transplantation in patients with augmented or diverted urinary systems presents unique challenges, including increased technical difficulties and infectious complications.
Traditional methods for creating augmented bladders for ureteral reimplantation require careful consideration of reservoir capacity, compliance, and pressure.
The search for innovative biomaterials aims to improve reconstructive surgical outcomes in urology.

Purpose:

To evaluate the safety and efficacy of using porcine small intestinal submucosa (SIS) as a biomaterial for creating augmented bladder reservoirs in kidney transplant recipients.
To assess the structural integrity and functional characteristics of SIS-derived augmented bladders in accommodating ureteral implantation.

Summary:

Porcine small intestinal submucosa (SIS) was utilized in four cases to construct augmented bladder reservoirs for kidney transplant recipients.
The SIS material successfully formed a three-layered (epithelial, muscular, adventitial) reservoir with normal pressure and good compliance.
The biomaterial is designed to degrade and be replaced by host tissue, offering a regenerative approach to bladder augmentation.

Impact:

This study suggests that SIS is a viable option for creating augmented bladder reservoirs, potentially mitigating risks associated with kidney transplantation in complex urinary anatomies.
The use of SIS may lead to improved outcomes and reduced graft loss in patients requiring ureteral reimplantation into augmented bladders.
Further research into SIS applications could advance reconstructive urology and transplantation surgery.