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Updated: Jun 6, 2026

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In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
[Multilocular cystic renal cell carcinoma: our experience]
Urologia
|November 19, 2010
Summary
Multilocular cystic renal cell carcinoma is a rare kidney cancer with slow growth, making it suitable for conservative treatment. Pre-operative diagnosis is challenging due to its similarity to other cystic kidney masses.
Area of Science:
- Nephrology
- Oncology
- Pathology
Context:
- The World Health Organization (WHO) now classifies multilocular cystic renal cell carcinoma as an independent entity.
- Cystic renal masses can originate from various causes, including malformations, acquired diseases, or tumors.
- Several neoplasms exhibit predominantly cystic growth, making differentiation difficult.
Purpose:
- To highlight the diagnostic challenges associated with multilocular cystic renal cell carcinoma.
- To discuss the pre- and intra-operative features of this rare renal malignancy.
- To emphasize the limitations of preoperative histological diagnosis for this specific tumor type.
Summary:
- Multilocular cystic renal cell carcinoma is a rare renal malignancy characterized by cystic growth and indolent behavior.
- Macroscopically, it resembles other cystic renal neoplasms, complicating preoperative diagnosis via imaging.
- Extemporaneous preoperative histological diagnosis is often not feasible due to the need for extensive sampling and potential requirement for immunohistochemistry.
Impact:
- Improved understanding of the diagnostic complexities of multilocular cystic renal cell carcinoma.
- Guidance for clinicians regarding the challenges in differentiating this tumor from other cystic renal lesions.
- Reinforces the importance of definitive histological and potentially immunohistochemical analysis for accurate diagnosis and treatment planning.
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