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Antibody to blood group glycosyltransferases in a patient transplanted with an ABO incompatible bone marrow
Y Kominato1, T Fujikura, H Takizawa
1Department of Legal Medicine, Toyama Medical and Pharmaceutical University, Japan.
In the plasma of a blood group B recipient who was transplanted with a blood group O bone marrow, we investigated an antibody to inhibit the activities of blood group A- and B-glycosyltransferases. When B lymphocytes from the patient were transformed with Epstein-Barr virus, a few clones producing antibodies to B-transferase were obtained.
In the plasma of a blood group B recipient who was transplanted with a blood group O bone marrow, we investigated an antibody to inhibit the activities of blood group A- and B-glycosyltransferases. When B lymphocytes from the patient were transformed with Epstein-Barr virus, a few clones producing antibodies to B-transferase were obtained.