Related Experiment Videos

A Case of Cryptococcal Lymphadenitis in an HIV-Infected Child

Eva Natukunda1, Victor Musiime, Francis Ssali

  • 1Joint Clinical Research Centre , Kampala, Uganda.

AIDS Research and Human Retroviruses
|November 20, 2010
PubMed

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Causative Organism
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Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the retrovirus to...