Related Experiment Video
Updated: Jun 6, 2026

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos
Published on: September 9, 2015
Brain abscess: an overview
Dattatraya Muzumdar1, Sukhdeep Jhawar, A Goel
1Department of Neurosurgery, Seth Gordhandas Sunderdas Medical College and King Edward VII Memorial Hospital, Parel, Mumbai, India. dmuzumdar@hotmail.com
Abstract:
Intracranial abscess is a formidable entity. Despite the advent of newer antibiotics and surgical strategies, the overall outcome and quality of life issues in brain abscess patients still remain a continuous challenge for the neurosurgical community. It is a direct interplay between the virulence of the offending microorganism and the immune response of the host. An analysis of our experience in the 289 cases of surgically treated pyogenic brain abscess is presented along with an overview of intra-cranial abscess of varied etiology and in different locations. The etiology, pathogenesis, radiological advances and treatment modalities of brain abscess are discussed in light of current literature.
Insights
Intracranial abscesses pose significant challenges despite advances in treatment. This study analyzes 289 surgically treated pyogenic brain abscess cases, reviewing etiology, pathogenesis, and treatment strategies.
Area of Science:
- Neurosurgery
- Infectious Diseases
- Neurology
Background:
- Intracranial abscesses remain a significant clinical challenge, impacting patient outcomes and quality of life.
- Despite advancements in antibiotics and surgical techniques, effective management requires understanding the interplay between microbial virulence and host immune response.
Purpose of the Study:
- To analyze the experience of surgically treating 289 pyogenic brain abscess cases.
- To provide an overview of intracranial abscesses concerning varied etiologies and locations.
- To discuss the etiology, pathogenesis, radiological findings, and treatment modalities in light of current literature.
Main Methods:
- Retrospective analysis of 289 surgically treated pyogenic brain abscess cases.
- Comprehensive literature review on intracranial abscesses.
Main Results:
- The study presents an analysis of surgically treated pyogenic brain abscess cases.
- An overview of intracranial abscesses with diverse etiologies and locations is provided.
Conclusions:
- Intracranial abscess management remains complex, necessitating a thorough understanding of causative factors and treatment options.
- Further research and clinical experience are crucial for improving outcomes in brain abscess patients.
Related Concept Videos
Brain Abscess l: Introduction
Bacterial Meningitis I: Introduction
Bacterial Meningitis II: Pathophysiology
Bacterial Meningitis
Acute Pyelonephritis II: Diagnostic Studies and Management
Acute Pyelonephritis I: Introduction