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Related Concept Videos

Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

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Related Experiment Video

Updated: Jun 6, 2026

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
10:32

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

Published on: March 23, 2014

Leprosy: down but not out.

Sandeep Sachdeva1, Zulfia Khan, Mohd Athar Ansari

  • 1JN Medical College, Aligarh Muslim University-Community Medicine, 3/115 A Durgabadi Marris Road Aligarh, Uttar Pradesh, India 202002. sandeepsemal@redffmail.com

Tropical Doctor
|November 20, 2010
PubMed
Summary

This study estimates annual leprosy incidence and identifies factors causing diagnostic delays in India. Early detection is crucial for managing this chronic, disabling disease.

Area of Science:

  • Medical research
  • Epidemiology
  • Public health

Background:

  • Leprosy is a chronic, disabling infectious disease with high endemicity in India.
  • Delayed diagnosis hinders effective case finding and management strategies.
  • Healthcare providers not recognizing disease manifestations promptly impacts control efforts.

Purpose of the Study:

  • To estimate the annual incidence of leprosy.
  • To identify confounding factors contributing to diagnostic delays.
  • To analyze these factors within a tertiary healthcare setting.

Main Methods:

  • Retrospective analysis of patient data.
  • Estimation of annual leprosy incidence rates.
  • Identification and analysis of factors associated with delayed diagnosis.

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ALS - Motor Neuron Disease: Mechanism and Development of New Therapies
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ALS - Motor Neuron Disease: Mechanism and Development of New Therapies

Published on: July 29, 2007

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Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
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Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

Published on: March 23, 2014

ALS - Motor Neuron Disease: Mechanism and Development of New Therapies
15:48

ALS - Motor Neuron Disease: Mechanism and Development of New Therapies

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Main Results:

  • The study quantifies the annual incidence of leprosy.
  • Key factors contributing to delayed diagnosis were identified.
  • Analysis provides insights into challenges in early leprosy detection.

Conclusions:

  • Understanding diagnostic delays is essential for improving leprosy control in India.
  • Targeted interventions can address identified barriers to timely diagnosis.
  • Enhanced healthcare provider education may reduce disease progression and transmission.