Effect of acute high-intensity interval exercise on postexercise biventricular function in mild heart failure
Corey R Tomczak1, Richard B Thompson, Ian Paterson
1Faculty of Rehabilitation Medicinem, 3-48 Corbett Hall, Univ. of Alberta, Edmonton, AB, Canada, T6G 2G4. corey.tomczak@ualberta.ca
Journal of Applied Physiology (Bethesda, Md. : 1985)
|November 20, 2010
Summary
High-intensity interval exercise improves heart function in mild heart failure patients. Acute exercise enhances left ventricular ejection fraction and preserves biventricular function, showing no impairment post-exercise.
Area of Science:
- Cardiology
- Exercise Physiology
- Cardiac Imaging
Background:
- Nonischemic mild heart failure (HF) affects biventricular function.
- The acute effects of high-intensity interval exercise (HIIE) on cardiac function in HF are not fully understood.
Purpose of the Study:
- To investigate the acute impact of HIIE on biventricular function in patients with nonischemic mild HF.
- To determine if HIIE leads to immediate post-exercise impairment in cardiac volumes and ejection fraction.
Main Methods:
- Cardiac magnetic resonance imaging (CMR) was used to assess biventricular function in nine patients with mild HF.
- Measurements included end-systolic volume (ESV), end-diastolic volume (EDV), ejection fraction (EF), and diastolic parameters before and after HIIE.
Main Results:
- HIIE led to a significant decrease in LV ESV and an increase in LV systolic annular velocity immediately post-exercise.
- LV EF increased by 2.4% at 30 minutes post-exercise. Right ventricular volumes showed similar responses.
- LV untwisting rate increased significantly post-exercise and remained elevated, while diastolic function was preserved.
Conclusions:
- Acute HIIE does not impair biventricular function in patients with nonischemic mild HF.
- HIIE may improve LV EF post-exercise through reduced afterload and maintained contractility.
- Enhanced LV untwisting may contribute to preserved diastolic function despite reduced preload post-exercise.
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