Related Experiment Video
Updated: Jun 6, 2026

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
Published on: August 16, 2021
Successful percutaneous coronary intervention for acute coronary syndrome in a patient with severe hemophilia a
Dong-Kie Kim1, Doo-Il Kim, Mo-Se Kim
1Division of Cardiology, Department of Internal Medicine, Inje University College of Medicine, Busan Paik Hospital, Busan, Korea.
Insights
Patients with hemophilia are now living longer, leading to an increased risk of coronary artery disease. This case study shows successful percutaneous coronary intervention for acute coronary syndrome in a severe hemophilia A patient.
Area of Science:
- Cardiology
- Hematology
- Interventional Cardiology
Background:
- Hemophilia patients historically had lower coronary artery disease (CAD) rates.
- Increased life expectancy in hemophilia management has led to a rise in CAD prevalence.
- Lack of established guidelines for CAD treatment, particularly coronary intervention, in hemophilia patients.
Purpose of the Study:
- To report a case of acute coronary syndrome (ACS) in a patient with severe hemophilia A.
- To demonstrate the successful application of percutaneous coronary intervention (PCI) in this patient population.
- To highlight the feasibility and potential of interventional cardiology approaches for CAD in hemophilia.
Main Methods:
- A case report of a severe hemophilia A patient presenting with ACS.
- Successful treatment with percutaneous coronary intervention.
- Management considerations specific to bleeding risk in hemophilia.
Main Results:
- The patient with severe hemophilia A and ACS underwent successful PCI.
- The intervention was performed without major bleeding complications.
- This demonstrates the technical feasibility of coronary intervention in hemophilia.
Conclusions:
- Percutaneous coronary intervention can be a safe and effective treatment for acute coronary syndrome in patients with severe hemophilia A.
- This case underscores the need for developing specific guidelines for managing coronary artery disease in hemophilia.
- Further research and case series are warranted to establish best practices for coronary intervention in this unique patient group.
Abstract:
Patients with hemophilia generally have a reduced frequency of coronary artery disease compared to the general population. As advances in the management of hemophilia have increased their life expectancy, the prevalence of coronary artery disease also has increased. However, there are no standard treatment guidelines for coronary artery disease in patients with hemophilia, especially in the field of coronary intervention. We report the case of a patient with severe hemophilia A who presented with acute coronary syndrome and was successfully treated with percutaneous coronary intervention.
Related Concept Videos
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Venous Thrombosis III: Interprofessional Care
Acute Coronary Syndrome IV: Interprofessional Care
Acute Coronary Syndrome I: Introduction
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

