Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
Schizophrenia01:17

Schizophrenia

Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.
Cognitive Development During Adolescence01:18

Cognitive Development During Adolescence

During adolescence, individuals experience significant cognitive development that enhances their understanding of others' emotions and thoughts, known as cognitive empathy. This period is marked by an increased ability to adapt to others' perspectives and a more nuanced understanding of others' mental states, a skill that is foundational for social problem-solving and conflict avoidance. The development of cognitive empathy relies heavily on the theory of mind — the recognition that people have...
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Erikson's Theory on Socioemotional Development during Adolescence01:17

Erikson's Theory on Socioemotional Development during Adolescence

Erik Erikson's fifth stage of psychosocial development, "identity versus role confusion," is crucial during adolescence (ages 12 to 18). In this stage, adolescents face the developmental task of forging a distinct personal identity, a process influenced by social, psychological, and biological changes typical of this period. Adolescents naturally explore different roles, behaviors, and ideologies as they navigate complex questions of self-concept, asking, "Who am I?" and "What is my place in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Belgian national registry on chronic pancreatitis: A prospective multi-centre study covering more than 800 patients in one year.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]·2017
Same author

[Diagnosis and management of pancreatitis].

Revue medicale de Bruxelles·2017
Same author

[The alexithymia questionnaire for children (AQC): Psychometric properties in a sample of 105 adolescents hospitalized in an adolescent psychiatric department].

L'Encephale·2016
Same author

An unusual case of haemolytic uraemic syndrome following endoscopic retrograde cholangiopancreatography rapidly improved with eculizumab.

Acta gastro-enterologica Belgica·2016
Same author

[Loneliness and adolescence: clinical implications and outlook. Literature review].

Revue medicale de Bruxelles·2016
Same author

[Munchausen by proxy syndrome].

Revue medicale de Bruxelles·2015
Same journal

[Breast cancer screening : a tool for informed decision making].

Revue medicale de Bruxelles·2018
Same journal

[Breast cancer screening : present situation and prospects].

Revue medicale de Bruxelles·2018
Same journal

[Guidelines in medical imaging : objectives, limits and radiation protection].

Revue medicale de Bruxelles·2018
Same journal

[How to avoid overmedicalization of the elderly patient ?]

Revue medicale de Bruxelles·2018
Same journal

[Ethical, pedagogical, socio-political and anthropological implications of quaternary prevention].

Revue medicale de Bruxelles·2018
Same journal

[New strategies in specific care for benign prostatic hypertrophy in older men].

Revue medicale de Bruxelles·2018
See all related articles

Related Experiment Video

Updated: Jun 6, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

[Schizophrenia at adolescence].

M Delhaye1

  • 1Clinique de Psychiatrie Infanto-Juvénile, Service de Psychiatrie, Hôpital Erasme, Bruxelles.

Revue Medicale De Bruxelles
|November 25, 2010
PubMed
Summary
This summary is machine-generated.

Diagnosing schizophrenia in adolescents is challenging, impacting development and psychosocial adaptation. Early intervention and understanding comorbid conditions like cannabis abuse are crucial for better outcomes.

More Related Videos

Social Defeat Stress Model for Adolescent C57BL/6 Male and Female Mice
07:15

Social Defeat Stress Model for Adolescent C57BL/6 Male and Female Mice

Published on: March 15, 2024

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
13:08

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Published on: December 2, 2015

Related Experiment Videos

Last Updated: Jun 6, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

Social Defeat Stress Model for Adolescent C57BL/6 Male and Female Mice
07:15

Social Defeat Stress Model for Adolescent C57BL/6 Male and Female Mice

Published on: March 15, 2024

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
13:08

Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia

Published on: December 2, 2015

Area of Science:

  • Psychiatry
  • Adolescent Mental Health
  • Neurodevelopmental Disorders

Context:

  • Schizophrenia diagnosis in adolescence presents significant clinical challenges.
  • Premorbid and family history are vital for accurate differential diagnosis.
  • Adolescent-onset schizophrenia has severe long-term consequences on development and psychosocial functioning.

Purpose:

  • To highlight the diagnostic difficulties of schizophrenia in adolescents.
  • To underscore the severe developmental and psychosocial impact of early-onset schizophrenia.
  • To review the limited data on effective therapies and the unproven efficacy of prevention strategies.

Summary:

  • Adolescent schizophrenia diagnosis is complex, often relying on premorbid and family history.
  • The disorder leads to detrimental effects on development and psychosocial adaptation, with a notable suicide risk.
  • Comorbidities such as cannabis abuse are relevant, yet data on productive therapies and prevention efficacy remain scarce.

Impact:

  • Emphasizes the need for improved diagnostic tools and therapeutic approaches for adolescent schizophrenia.
  • Highlights the critical importance of addressing psychosocial and developmental trajectories in affected individuals.
  • Underscores the urgent need for research into effective prevention and treatment strategies for early-onset schizophrenia.