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[Effects of finasteride on hematuria associated with benign prostatic hyperplasia: a meta-analysis]

Yi Jiang1, Yong-Fu Long

  • 1Department of Urology, Central Hospital of Shaoyang, Shaoyang, Hunan 422000, China. jy3485@sina.com

Zhonghua Nan Ke Xue = National Journal of Andrology
|November 25, 2010
PubMed

Insights

Finasteride significantly reduces hematuria in men with benign prostatic hyperplasia (BPH). This study confirms finasteride

Area of Science:

  • Urology
  • Pharmacology

Context:

  • Benign prostatic hyperplasia (BPH) is a common condition in aging men.
  • Hematuria is a distressing symptom associated with BPH.

Purpose:

  • To systematically evaluate the efficacy of finasteride in managing BPH-associated hematuria.
  • To synthesize evidence from randomized controlled trials on finasteride's effect on hematuria.

Summary:

  • A systematic review and meta-analysis of randomized controlled trials was conducted.
  • Finasteride treatment resulted in a significant reduction in hematuria incidence compared to placebo over 12 months.
  • The observed effect was statistically significant (OR 0.11, 95% CI: 0.06-0.21).

Impact:

  • Finasteride demonstrates therapeutic and preventive benefits for BPH-related hematuria.
  • Findings support finasteride as a treatment option for men experiencing hematuria due to BPH.
  • Highlights the need for further large-scale, multicenter trials to solidify these conclusions.
Abstract

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