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Building addressable libraries: the use of "safety-catch" linkers on microelectrode arrays
Bo Bi1, Karl Maurer, Kevin D Moeller
1Department of Chemistry, Washington University in St. Louis, St. Louis, Missouri 63130, USA.
Journal of the American Chemical Society
|November 25, 2010
Abstract:
A "safety-catch" linker strategy has been used to site-selectively cleave and characterize molecules from a microelectrode array. The linkers are attached to the array by means of an ester and contain either a protected amine or protected alcohol nucleophile that can be released using acid generated at the microelectrodes.

