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Related Concept Videos

Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
Aging01:26

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...

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Updated: Jun 6, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

Aging and hypertension.

Motoki Fukutomi1, Kazuomi Kario

  • 1Department of Cardiology, Yamaguchi Grand Medical Center, 77 Osaki, Hofu, Yamaguchi 747-8511, Japan.

Expert Review of Cardiovascular Therapy
|November 25, 2010
PubMed
Summary
This summary is machine-generated.

Aging significantly increases hypertension risk. Managing blood pressure in older adults is crucial, requiring 24-hour ambulatory blood pressure monitoring to address unique age-associated hypertension patterns.

Related Experiment Videos

Last Updated: Jun 6, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

Area of Science:

  • Gerontology
  • Cardiovascular Medicine
  • Nephrology

Background:

  • Aging is a primary risk factor for hypertension development and progression.
  • The aging population in developed countries necessitates urgent strategies for hypertension management in the elderly.
  • Age-related changes in organ systems critically influence blood pressure regulation.

Purpose of the Study:

  • To highlight the urgency of addressing hypertension in the elderly.
  • To explain the physiological basis of age-associated blood pressure elevation.
  • To emphasize the need for comprehensive blood pressure assessment in older adults.

Main Methods:

  • Review of age-associated physiological changes impacting blood pressure.
  • Analysis of hypertension phenotypes in the elderly, including nocturnal and morning hypertension.
  • Assessment of the role of ambulatory blood pressure monitoring (ABPM) for 24-hour evaluation.

Main Results:

  • Age-related organ system decline contributes to elevated blood pressure.
  • Cardiovascular aging leads to diverse hypertension phenotypes in the elderly.
  • 24-hour ABPM is essential for accurate detection and treatment of age-associated hypertension.

Conclusions:

  • Effective management of hypertension in the elderly requires understanding age-related physiological changes.
  • Specific hypertension patterns in older adults necessitate tailored monitoring approaches.
  • Ambulatory blood pressure monitoring provides critical data for optimizing hypertension care in aging populations.