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Updated: Jun 6, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
A mandatory intercalated degree programme: revitalising and enhancing academic and evidence-based medicine
John P Collins1, Stephen Farish, Janet S McCalman
1University of Melbourne, Australia. john.collins@nds.ox.ac.uk
Background:
Recruitment of medical graduates to research careers is declining. Expansion of medical knowledge necessitates all graduates be equipped to critically evaluate new information. To address these challenges, a mandatory intercalated degree programme was introduced as part of curriculum reform.
Aims:
To review the place on intercalated degrees, the methods available for learning about research and to analyse experience with a new university programme focusing on research.
Methods:
A literature review followed by the analysis of experience with eight cohorts of students who had completed the new programme.
Results:
A total of 1599 students completed the programme. Laboratory-based research was the most common choice followed by clinical research, population health, epidemiology, medical humanities and mental health. Also, 93% of students spent over 75% of their time undertaking research. Sixty-three students published their research, half as first authors. Students and coordinators support the programme. Learning about research during the postgraduate phase is variable and frequently left to individual choice.
Conclusion:
Intercalating an additional degree focusing on research can achieve a number of learning objectives but demands a level of maturity, autonomy and preparedness, not uniformly present in students undertaking a mandatory intercalated programme. A more realistic goal is the development of 'research-mindedness' amongst all students.
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