Related Experiment Video
Updated: Jun 6, 2026

Contrast Imaging in Mouse Embryos Using High-frequency Ultrasound
Published on: March 4, 2015
Contrast-enhanced sonography as a novel tool for assessment of vascular malformations
Yukiko Oe1, Lauren Orr2, Sherelle Laifer-Narin3
1Department of Cardiology, Columbia University, New York, NY, USA.
Insights
Contrast-enhanced sonography offers a novel, cost-effective imaging tool for pediatric vascular malformations. This method accurately defines arteriovenous shunting, potentially reducing radiation exposure and improving patient outcomes.
Area of Science:
- Medical Imaging
- Pediatric Radiology
- Vascular Surgery
Background:
- Vascular malformations with arteriovenous shunts cause significant disability and pain.
- Current treatment often requires serial procedures.
- An optimized, low-radiation imaging modality is needed for pediatric patients.
Purpose of the Study:
- To introduce contrast-enhanced sonography as a novel imaging tool.
- To evaluate its utility in defining vascular anatomy and arteriovenous shunting.
- To assess its potential for cost reduction and decreased radiation exposure.
Main Methods:
- Utilized contrast-enhanced sonography.
- Applied to a pediatric patient with a symptomatic vascular malformation.
- Focused on defining vascular anatomy and localizing arteriovenous shunting.
Main Results:
- Successfully visualized vascular anatomy.
- Accurately localized arteriovenous shunting.
- Demonstrated the feasibility of the technique in a pediatric case.
Conclusions:
- Contrast-enhanced sonography is a promising imaging application for vascular malformations.
- This method may reduce radiation exposure and healthcare costs.
- Provides unique insights into arteriovenous shunting in pediatric patients.
Background:
Vascular malformations with arteriovenous shunt components can cause significant disability, chronic pain, and functional impairment. Effective treatment may require serial procedures, yet an imaging modality optimized to control cost and reduce radiation exposure in this predominantly pediatric population has not yet been identified.
Methods And Results:
We describe the use of contrast-enhanced sonography as a novel tool to define vascular anatomy and localize arteriovenous shunting in a young patient with a symptomatic vascular malformation.
Conclusions:
This method may effectively reduce radiation exposure and cost, and additionally provide unique information about arteriovenous shunting, offering a novel imaging application for patients with these conditions.
Related Concept Videos
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
Imaging Studies VII: Vascular Imaging
Ultrasonography
During an ultrasonography procedure, a handheld device called a...
Imaging Studies II: Ultrasonography
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Assessment of Diffusion and Perfusion
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...

