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Updated: Jun 6, 2026
Regenerative Peripheral Nerve Interface: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain
Published on: March 15, 2024
[To explore treatment of neurogenic tumors of the peripheral nerve]
Cang Liu1, Jing Zhang, Wen-qing Jia
1Department of Neurosurgery, Beijing Friendship Hospital Affiliated to Capital Medical University, Beijing 100050, China. Lzang2985@yahoo.com.cn
Objective:
To discuss the clinical features and surgical tactics of neurogenic tumors external spinal canal.
Methods:
The investigators retrospectively analyzed the clinical data of 56 cases with neurogenic tumors external spinal canal as confirmed by pathology at our department from January 2000 to June 2010. And the follow-up results were tracked. Among the patients, 51 cases underwent microsurgery and 5 cases routine retro-peritoneal operation.
Results:
Fifty cases received total resection and 5 cases subtotal resection. Partial tumor removal was performed in 1 case with multiple Schwannoma only because nerve roots were densely distributed around the tumor. Postoperative complications included declining myodynamia (n = 3), extremity pain (n = 2), topical sensory disturbance (n = 7), hoarseness (n = 5), ipsilateral facioplegia & hypophysis (n = 1) and Horner's syndrome (n = 2). Thirty-six cases had a follow-up period of 0.5 year to 10 years. No in situ recurrence was found in 34 cases. Two cases with in situ recurrence were re-operated. There was no operative death.
Conclusion:
The surgery of neurogenic tumors external spinal canal can improve the symptoms and quality of life for the patients. A better outcome is based on anatomic familiarity and skilled micromanipulation. The key aspects of tumor resection are a maximal protection of proximal important vessels and nerves and thorough tumor dissection.
