Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Urinary Tract Calculi III: Medical Management01:30

Urinary Tract Calculi III: Medical Management

The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The clinical application of parenteral nutrition with Omega-3 fatty acids in patients after gastrectomy: a retrospective cohort study and cost-effectiveness analysis.

Lipids in health and disease·2026
Same author

Integrated diagnostic evaluation of multiple malignant neoplasms via <sup>99m</sup>Tc-MDP three-phase bone imaging: A case report.

Oncology letters·2025
Same author

Preoperative model for predicting early recurrence in hepatocellular carcinoma patients using radiomics and deep learning: A multicenter study.

World journal of gastrointestinal oncology·2025
Same author

Immune checkpoint inhibitors plus anti-angiogenesis in patients with resected high-risk hepatitis B virus-associated hepatocellular carcinoma.

World journal of gastrointestinal oncology·2025
Same author

Evaluating microvascular invasion in hepatitis B virus-related hepatocellular carcinoma based on contrast-enhanced computed tomography radiomics and clinicoradiological factors.

World journal of gastroenterology·2024
Same author

Meta-analysis of the GALAD model for diagnosing primary hepatocellular carcinoma.

Technology and health care : official journal of the European Society for Engineering and Medicine·2024

Related Experiment Video

Updated: Jun 6, 2026

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
06:09

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis

Published on: July 18, 2017

[A modified rat model for infection-induced stone formation].

Jian-lin Lü1, Xi-zhao Sun, Huai-jun Zhu

  • 1Department of Urology, Drum Tower Hospital, Nanjing University, Nanjing 210008, China. ljlyy01@163.com

Zhonghua Yi Xue Za Zhi
|November 25, 2010
PubMed
Summary

A new rat model effectively induces bladder stones by introducing Proteus mirabilis-contaminated wires, offering a valuable tool for studying infection stones.

Area of Science:

  • Urology
  • Infectious Diseases
  • Animal Models

Background:

  • Urinary tract infections, particularly those caused by Proteus mirabilis, are a significant cause of bladder stone formation.
  • Developing reliable animal models is crucial for understanding the pathogenesis and treatment of infection stones.

Purpose of the Study:

  • To establish and validate a novel, modified rat model for inducing infection-associated bladder stone formation.
  • To assess the efficacy and characteristics of stone formation in the new model.

Main Methods:

  • Adult male Sprague Dawley rats were divided into three groups: model (n=12), sham (n=8), and control (n=4).
  • In the model group, a Proteus mirabilis-contaminated metal wire was implanted into the bladder lumen via a guided puncture.
  • Bladders were examined 21 days post-implantation for urolithiasis.

More Related Videos

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
09:52

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites

Published on: August 8, 2014

Related Experiment Videos

Last Updated: Jun 6, 2026

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
06:09

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis

Published on: July 18, 2017

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
09:52

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites

Published on: August 8, 2014

Main Results:

  • All rats in the model group (100%) developed struvite bladder stones within 21 days.
  • No stone formation was observed in the sham or control groups.
  • The stones were confirmed as struvite by infrared spectroscopy and optical crystallography.

Conclusions:

  • This modified rat model demonstrates high efficiency in inducing infection-associated bladder stones.
  • The model exhibits reduced trauma and faster recovery compared to previous methods.
  • It serves as a promising platform for future research into infection stones.