Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Contemporary Outcomes of Temporary Mechanical Circulatory Support Use in Ischemic Ventricular Septal Defect: A U.S. Multi-Center Analysis.

The Annals of thoracic surgeryยท2026
Same author

Two variations of Commando-Nicks approach for calcified aortic and mitral valve disease.

Multimedia manual of cardiothoracic surgery : MMCTSยท2026
Same author

Incidence and Management of Access Site Infection Following Trans-Axillary Implant of a Microaxial Left Ventricular Assist Device.

Artificial organsยท2026
Same author

Optimizing the circuit: A critical enhancement at the 2025 NYC Marathon.

The American journal of emergency medicineยท2026
Same author

Simultaneous Heart and Kidney Transplantation Using Circulatory Death Donors: Are Kidney Graft Outcomes Comparable With Brain Death Donors?

Transplantation directยท2025
Same author

Redo axillary artery cannulation in aortic reoperations: Technical variations and implications for optimal outcomes.

JTCVS techniquesยท2025
Same journal

Bridging Pediatric and Young Adult Cancer Survivorship: Defining the Thoracic Surgeon's Role Across the Continuum.

The Journal of thoracic and cardiovascular surgeryยท2026
Same journal

Beyond compensatory expansion: Extending 3-dimensional computed tomography volumetry toward lung-preserving local therapy.

The Journal of thoracic and cardiovascular surgeryยท2026
Same journal

A CALL FOR STANDARDIZATION OF HYBRID ARCH FROZEN ELEPHANT TRUNK OUTCOMES REPORTING.

The Journal of thoracic and cardiovascular surgeryยท2026
Same journal

Pediatric Mitral Valve Surgery: Current Practice from the European Congenital Heart Surgeons Association Congenital Database Analysis.

The Journal of thoracic and cardiovascular surgeryยท2026
Same journal

Rethinking Failure to Rescue in Cardiac Surgery.

The Journal of thoracic and cardiovascular surgeryยท2026
Same journal

Undersized Fontan conduits are not without risk.

The Journal of thoracic and cardiovascular surgeryยท2026
See all related articles

Related Experiment Video

Updated: Jun 6, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

Acute aortic syndrome.

Steven L Lansman1, Paul C Saunders, Ramin Malekan

  • 1Westchester Medical Center, New York Medical College, Valhalla, NY, USA. LansmanS@WCMC.com

The Journal of Thoracic and Cardiovascular Surgery
|November 25, 2010
PubMed
Summary
This summary is machine-generated.

Acute aortic syndrome, encompassing penetrating aortic ulcers and intramural hematomas, presents with aortic pain. This review focuses on the management of these serious aortic conditions.

More Related Videos

Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice
07:21

Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice

Published on: September 28, 2015

Related Experiment Videos

Last Updated: Jun 6, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice
07:21

Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice

Published on: September 28, 2015

Area of Science:

  • Cardiovascular Medicine
  • Vascular Surgery
  • Diagnostic Imaging

Background:

  • Acute aortic syndrome (AAS) is a spectrum of life-threatening conditions characterized by aortic pain.
  • Key components include penetrating aortic ulcer (PAU) and intramural hematoma (IMH).
  • These conditions share similarities with aortic dissection but have distinct pathophysiological features.

Purpose of the Study:

  • To review current literature on acute aortic syndrome.
  • To elucidate the relationship between PAU, IMH, and aortic dissection.
  • To discuss contemporary management strategies for AAS.

Main Methods:

  • Comprehensive literature search of relevant studies on AAS.
  • Analysis of pathophysiological mechanisms of PAU and IMH.
  • Review of clinical presentations and diagnostic findings.
  • Synthesis of evidence-based management guidelines.

Main Results:

  • PAU involves atherosclerotic plaque erosion into the aortic media.
  • IMH is a contained hemorrhage within the aortic wall, potentially a variant of dissection.
  • Both PAU and IMH can mimic or be associated with aortic dissection, requiring careful differentiation.
  • Management strategies vary based on specific diagnosis and clinical presentation.

Conclusions:

  • Accurate diagnosis of PAU and IMH is crucial for appropriate management.
  • Understanding the relationship between these entities and aortic dissection guides treatment decisions.
  • Optimal management of AAS requires a multidisciplinary approach, integrating medical, endovascular, and surgical options.