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Updated: Jun 6, 2026

A Murine Tail Lymphedema Model
Published on: February 10, 2021
[Inflammatory bowel disease and lower limb lymphedema: a fortuitous association?]
M Arrault1, M Blanchard, S Vignes
1Unité de lymphologie, hôpital Cognacq-Jay, 15 rue Eugène-Millon, Paris, France.
Introduction:
Extra-intestinal manifestations of chronic inflammatory bowel disease (CIBD) are various. Cases of genital lymphedema has previously been reported in Crohn's disease.
Case Reports:
We report two women aged 57 and 68 years who presented with a lower limb lymphedema 8 and 20 years after a diagnosis of CIBD (Crohn's disease and ulcerative colitis), respectively. At the time of diagnosis of lymphedema, CIBD was asymptomatic.
Conclusion:
Pathophysiological mechanisms of this rare manifestation are unclear and lymphedema outcome is unrelated to CIBD activity.
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