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Updated: Jun 6, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
Published on: August 26, 2014
High-definition and filter-aided colonoscopy
Jenny Sauk1, Arthur Hoffman, Sharmila Anandasabapathy
1The Henry D. Janowitz Division of Gastroenterology, Mount Sinai School of Medicine, 1 Gustave Levy Place, Box 1069, New York, NY 10029, USA.
Abstract:
New high-resolution colonoscopes and filter technologies are allowing us to visualize more lesions and better characterize lesions within the gastrointestinal tract. In light of recent findings that flat and serrated lesions are more likely to contain invasive cancer and that even small lesions (5-10 mm) may contain advanced histology, detecting these lesions earlier with improved optical technologies may help decrease the rate of interval cancers after colonoscopy. With the limited accuracy of white-light colonoscopy (59%-84%) in distinguishing non-neoplastic lesions from neoplastic lesions, these new technologies can help us improve our abilities to risk stratify patients and determine more precise surveillance intervals.
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