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Updated: Jun 6, 2026
07:46
Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat
Published on: June 4, 2012
Two successfully treated cases of Staphylococcus lugdunensis endocarditis
Kalliopi-Stavroula Chatzigeorgiou1, Christina Ikonomopoulou, Sofia Kalogeropoulou
1Laboratory of Clinical Microbiology, Attikon University Hospital, University of Athens, Medical School, Athens-Haidari, Greece.
Diagnostic Microbiology and Infectious Disease
|November 25, 2010
Summary
Staphylococcus lugdunensis prosthetic valve endocarditis is rare and dangerous. However, combined antimicrobial and surgical treatment led to full recovery in two severe cases involving a prosthetic aortic valve and pacemaker lead.
Area of Science:
- Infectious Diseases
- Cardiology
- Medical Device Infections
Background:
- Prosthetic valve endocarditis (PVE) and pacemaker lead endocarditis (PLE) are serious infections.
- Staphylococcus lugdunensis is an uncommon but potentially virulent pathogen in endocarditis.
Observation:
- Two rare cases of endocarditis caused by Staphylococcus lugdunensis are presented.
- One case involved a prosthetic aortic valve; the other involved a pacemaker lead.
Findings:
- Both patients presented with severe disease and delayed diagnosis.
- Combined antimicrobial therapy and surgical intervention were crucial for successful treatment.
- Complete recovery was achieved in both cases despite the initial severity.
Implications:
- This study highlights the importance of considering Staphylococcus lugdunensis in prosthetic device infections.
- Aggressive combined treatment strategies can lead to favorable outcomes even in complex cases.
- Early diagnosis and intervention are critical for managing prosthetic valve and pacemaker lead endocarditis.
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