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Related Concept Videos

American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...

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Updated: Jun 6, 2026

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates
13:55

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates

Published on: January 27, 2019

Chagas' disease and solid organ transplantation.

, Domingo Casadei

    Transplantation Proceedings
    |November 25, 2010
    PubMed
    Summary

    This review covers Chagas

    Area of Science:

    • Transplant medicine
    • Infectious diseases
    • Parasitology

    Background:

    • Chagas' disease poses risks in organ transplantation.
    • Transmission can occur from infected donors to recipients.
    • Management strategies are crucial for patient outcomes.

    Purpose of the Study:

    • To review current data on Chagas' disease in transplant recipients.
    • To present guidelines for managing transplantation involving Chagas' disease.
    • To incorporate expert experience from leading transplant centers.

    Main Methods:

    • Literature review of published data.
    • Inclusion of unpublished data from Argentine transplant centers.
    • Formulation of consensus guidelines by a collaborative consortium.

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    Parasite Induced Genetically Driven Autoimmune Chagas Heart Disease in the Chicken Model
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    Parasite Induced Genetically Driven Autoimmune Chagas Heart Disease in the Chicken Model

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    Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates
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    Published on: January 27, 2019

    In Vitro Drug Screening Against All Life Cycle Stages of Trypanosoma cruzi Using Parasites Expressing β-galactosidase
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    Main Results:

    • Summarizes risks and outcomes for transplant recipients with Chagas' disease.
    • Details management protocols for infected donors and recipients.
    • Provides evidence-based recommendations for clinical practice.

    Conclusions:

    • Standardized pretransplant evaluation is essential.
    • Post-transplant monitoring and management are critical.
    • Collaborative efforts improve care for transplant patients with Chagas' disease.