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Successful thrombolysis after pulmonary endarterectomy

Kathrin I Schmidt1, Peter Fries, Susanne K Feldner

  • 1Department of Thoracic and Cardiovascular Surgery, University Hospital of Saarland, Homburg/Saar, Germany.

The Annals of Thoracic Surgery
|November 25, 2010
PubMed

We report the case of a 51-year-old woman who underwent pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension. On postoperative day 1 she developed bilateral pulmonary thrombosis due to preoperatively undiagnosed heparin-induced thrombocytopenia. Systemic thrombolytic therapy with alteplase on postoperative days 5 and 6 resulted in marked clinical improvement. To our knowledge this is the first report of successful thrombolysis of pulmonary thrombosis due to heparin-induced thrombocytopenia after pulmonary endarterectomy.

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