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Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
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Bladder pain syndrome.

Philip Hanno1, Jørgen Nordling, Magnus Fall

  • 1Perelman Center for Advanced Medicine, Hospital of the University of Pennsylvania, West Pavilion 3rd Floor, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA. hannop@uphs.upenn.edu

The Medical Clinics of North America
|November 25, 2010
PubMed
Summary
This summary is machine-generated.

Bladder pain syndrome (BPS) is a complex condition causing chronic pelvic pain linked to the bladder. It affects many women and is often misdiagnosed, making diagnosis and treatment difficult.

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Area of Science:

  • Urology
  • Pain Medicine

Background:

  • Bladder pain syndrome (BPS) is a complex condition characterized by chronic pelvic pain, pressure, or discomfort related to the urinary bladder.
  • It is diagnosed when symptoms persist for at least 6 weeks, excluding other potential causes.
  • BPS affects up to 3% of the female population in the US, with a significant female-to-male ratio of 5:1.

Purpose of the Study:

  • To elucidate the diagnostic challenges and common misdiagnoses associated with Bladder Pain Syndrome.
  • To highlight the prevalence and demographic distribution of BPS.

Main Methods:

  • Diagnosis by exclusion of confusable diseases.
  • Symptom assessment for chronic pelvic pain and urinary issues.

Main Results:

  • BPS is a diagnosis of exclusion, requiring symptoms for over 6 weeks.
  • Prevalence estimates suggest up to 3% of US women are affected.
  • Common misdiagnoses include psychological disorders, overactive bladder, and chronic urinary infections.

Conclusions:

  • Bladder pain syndrome presents a significant diagnostic and therapeutic challenge.
  • Misdiagnosis is common, leading to delayed or inadequate treatment for affected individuals.
  • Increased awareness and accurate diagnostic criteria are crucial for managing BPS.