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Related Concept Videos

General Anesthesia: Overview01:24

General Anesthesia: Overview

Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions01:24

Drug Accumulation During Multiple Dosing: Intermittent IV Infusions

Intermittent intravenous (IV) infusion is a method of drug administration where medications are delivered over short infusion periods followed by intervals of no drug delivery. This approach helps to prevent sustained high drug concentrations in the bloodstream, reducing the risk of adverse effects associated with prolonged exposure. Unlike continuous infusion, steady-state concentrations may not be achieved during a single dosing cycle but can be reached through repeated...

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Related Experiment Video

Updated: Jun 6, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Anaesthesia synchronization software: target controlled infusion system evaluation.

Nadja Bressan1, A Paulo Moreira, Pedro Amorim

  • 1University of Porto, Faculty of Engineering, Department of Electrical and Computer Engineering, Portugal. nadja.bressan@fe.up.pt

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
|November 25, 2010
PubMed
Summary
This summary is machine-generated.

This study validated the Anaesthesia Synchronization Software (ASYS) Target Controlled Infusion (TCI) system. ASYS demonstrated robust and accurate performance in a clinical setting, ensuring reliable computer-to-infusion device communication.

Related Experiment Videos

Last Updated: Jun 6, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Area of Science:

  • Anesthesiology
  • Medical Informatics
  • Pharmacometrics

Background:

  • Target Controlled Infusion (TCI) systems utilize pharmacokinetic (Pk) and pharmacodynamic (Pd) models for anesthesia drug delivery.
  • Previous research has compared manual titration with TCI, evaluated TCI control algorithms, and assessed Pk/Pd models within TCI systems.

Purpose of the Study:

  • To validate the performance of the Anaesthesia Synchronization Software (ASYS) TCI system in a clinical environment.
  • To assess the communication consistency between the computer and infusion device.
  • To evaluate the real-time controller performance of the ASYS TCI system.

Main Methods:

  • The study involved a set of tests designed to validate the TCI system's performance as a computer-aided tool.
  • Evaluation focused on communication consistency and real-time controller performance in a clinical setup.
  • Quantitative and qualitative measures were employed to assess the software's robustness and accuracy.

Main Results:

  • The ASYS TCI system demonstrated reliable communication between the computer and the infusion device.
  • The controller performance was evaluated in real-time, providing evidence of accuracy.
  • The study provided quantitative and qualitative data supporting the software's robustness.

Conclusions:

  • The Anaesthesia Synchronization Software (ASYS) TCI system is robust and accurate for clinical use.
  • The system ensures reliable communication and effective controller performance.
  • This validation supports the use of ASYS in clinical environments for anesthesia management.