LPV control of glucose for Diabetes type I
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Updated: Jun 6, 2026

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
R S Sánchez Peña1, A S Ghersin
1Centro de Sistemas y Control, Department of Physics & Mathematics Buenos Aires Institute of Technology (ITBA), Argentina. rsanchez@itba.edu.ar
Abstract:
This paper considers the problem of automatically controlling the glucose level in a Diabetes type I patient. Three issues have been considered: model uncertainty, time-varying/nonlinear phenomena and controller implementation. To that end, the dynamical model of the insulin/glucose relation is framed as a Linear Parameter Varying system and a controller is designed based on it. In addition, this framework allows not only a better performance than other classical methods, but also provides stability and performance guarantees. Design computations are based on convex Linear Matrix Inequality (LMI) optimization. Implementation is based on a low order controller whose dynamics adapts according to the glucose levels measured in real-time.
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