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Related Experiment Video

Updated: Jun 6, 2026

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation
10:52

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation

Published on: October 2, 2015

3D microprobes for deep brain stimulation and recording.

Arash A Fomani1, Maryam Moradi, Souhile Assaf

  • 1Electrical and Computer Engineering Department, University of Waterloo, Ontario N2L 3G1, Canada. aakhavan@uwaterloo.ca

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
|November 25, 2010
PubMed
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New 3D multi-channel microprobes offer precise deep brain stimulation (DBS) and recording capabilities. These flexible devices enable high-density electrode placement for advanced neurological applications.

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Materials Science

Background:

  • Deep brain stimulation (DBS) requires advanced electrode technology for precise neural modulation.
  • Current microprobe technology faces limitations in achieving high channel density and precise electrode site definition.

Purpose of the Study:

  • To introduce a novel generation of three-dimensional (3D) multi-channel microprobes for DBS.
  • To demonstrate the fabrication and capabilities of these microprobes for both stimulation and recording.

Main Methods:

  • Fabrication of planar flexible microprobes using sub-micrometer resolution lithography.
  • Assembly of microprobes onto cylindrical polyurethane shafts (radius as low as 350 microm).
  • Characterization of microprobe dimensions and electrode site density.

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Related Experiment Videos

Last Updated: Jun 6, 2026

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation
10:52

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation

Published on: October 2, 2015

Deep Brain Stimulation with Simultaneous fMRI in Rodents
11:09

Deep Brain Stimulation with Simultaneous fMRI in Rodents

Published on: February 15, 2014

Large-scale Recording of Neurons by Movable Silicon Probes in Behaving Rodents
17:37

Large-scale Recording of Neurons by Movable Silicon Probes in Behaving Rodents

Published on: March 4, 2012

Main Results:

  • Successful development of a 3D microprobe with 16 stimulating and 16 recording channels.
  • Precisely defined stimulation sites (100 microm × 1.5 mm) and recording sites (20 microm × 20 microm).
  • Demonstrated high electrode site density enabled by lithographic fabrication.

Conclusions:

  • The new 3D multi-channel microprobes provide enhanced capabilities for DBS applications.
  • This technology offers precise control over stimulation and recording parameters.
  • The fabrication method allows for high-density electrode arrays suitable for advanced neural interfacing.