Wireless remote monitoring of myocardial ischemia using reconstructed 12-lead ECGs

Area of Science:

• Cardiology
• Biomedical Engineering
• Medical Device Technology

Background:

• Coronary artery disease (CAD) monitoring requires accurate electrocardiogram (ECG) data.
• Traditional 12-lead ECGs (12L) can be cumbersome, especially during exercise testing.
• There is a need for portable, patient-activated ECG devices for continuous monitoring.

Purpose of the Study:

• To evaluate the accuracy of the CardioBip (CB) device in reconstructing and transmitting 12-lead ECGs (12CB) in CAD patients.
• To assess the utility of 12CB for detecting ST segment changes indicative of exercise-induced ischemia.
• To determine if CB is a viable tool for monitoring CAD patients during exercise treadmill testing (ETT).

Main Methods:

• Comparison of CardioBip's 12CB with simultaneous 12-lead ECGs (12L) in CAD patients.
• Inclusion of pre- and post-exercise treadmill testing (ETT) to capture dynamic ECG changes.
• Utilizing a hand-held, patient-activated device with 5 contact points for ECG acquisition.

Main Results:

• The CardioBip device successfully reconstructed and wirelessly transmitted 12-lead ECGs (12CB) in CAD patients during ETT recovery.
• The 12CB effectively captured ST segment changes associated with exercise-induced ischemia, comparable to traditional 12L ECGs.
• The device demonstrated accuracy in monitoring cardiac conditions during stress testing.

Conclusions:

• CardioBip (CB) is a promising technology for accurate 12-lead ECG (12CB) acquisition and transmission in coronary artery disease (CAD) patients.
• The device shows potential for evaluating ST segment changes and monitoring exercise-induced ischemia.
• CB offers a patient-activated, wireless solution for cardiac monitoring during exercise treadmill testing (ETT).