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Published on: February 13, 2021
Dynamic modeling of the vascular system in the state-space
Jorge E Monzon1, Maria I Pisarello, Carlos Alvarez Picaza
1Universidad Nacional del Nordeste, Corrientes, Argentina. jemonzon@exa.unne.edu.ar
Summary
This study models arterial wall compliance changes using state equations. The model effectively distinguishes between hypertensive and normotensive individuals based on cardiac dynamics.
Area of Science:
- Biomedical Engineering
- Cardiovascular Physiology
- Control Theory
Background:
- Cardiac dynamics can be represented in state-space using modern control theory.
- Arterial wall compliance changes influence vascular system operation, acting as a cushioning effect.
Purpose of the Study:
- To model the impact of arterial wall compliance variations using state equations.
- To differentiate between hypertensive and normotensive subjects based on modeled arterial dynamics.
Main Methods:
- Utilizing state equations to represent arterial wall dynamics.
- Analyzing model characteristics and parameters derived from compliance variations.
Main Results:
- The developed model captures the effects of compliance changes on the arterial wall.
- Distinct dynamic characteristics and parameters were identified for hypertensive and normotensive groups.
Conclusions:
- The state-space model effectively distinguishes hypertensive from normotensive subjects.
- This approach offers a quantitative method for analyzing cardiovascular compliance in clinical settings.
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