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Updated: Jun 6, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Classification of melanocytic skin lesions from non-melanocytic lesions
Hitoshi Iyatomi1, Kerri-Ann Norton, M Celebi
1Faculty of Engineering, Hosei University, 3-7-2 Kajino-cho Koganei, 184-8522, Tokyo, Japan. iyatomi@hosei.ac.jp
Abstract:
In this paper, we present a classification method of dermoscopy images between melanocytic skin lesions (MSLs) and non-melanocytic skin lesions (NoMSLs). The motivation of this research is to develop a pre-processor of an automated melanoma screening system. Since NoMSLs have a wide variety of shapes and their border is often ambiguous, we developed a new tumor area extraction algorithm to account for these difficulties. We confirmed that this algorithm is capable of handling different dermoscopy images not only those of NoMSLs but also MSLs as well. We determined the tumor area from the image using this new algorithm, calculated a total 428 features from each image, and built a linear classifier. We found only two image features, "the skewness of bright region in the tumor along its major axis" and "the difference between the average intensity in the peripheral part of the tumor and that in the normal skin area using the blue channel" were very efficient at classifying NoMSLs and MSLs. The detection accuracy of MSLs by our classifier using only the above mentioned image feature has a sensitivity of 98.0% and a specificity of 86.6% in a set of 107 non-melanocytic and 548 melanocytic dermoscopy images using a cross-validation test.
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