Related Experiment Video
Updated: Jan 18, 2026
Application of an Amplitude-integrated EEG Monitor Cerebral Function Monitor to Neonates
Published on: September 6, 2017
Time-variant analysis of linear and non-linear phase couplings of and between frequency components of EEG burst
Matthias Wacker1, Peter Putsche, Herbert Witte
1Institute for Medical Statistics, Computer Sciences and Documentation, Bernstein Group for Computational Neuroscience Jena, Friedrich Schiller University Jena, Germany. matthias.wacker@mti.uni-jena.de
Abstract:
Time-variant (tv) phase-locking and synchronization characteristics of and between low-frequency (≤ 1.5 Hz) and high-frequency EEG oscillations (≥ 3.5 Hz) of the tracé alternant (TA) pattern in full-term newborns have been quantified to explore the origin of quadratic phase coupling (QPC, as non-linear phase coupling measure) between the frequency ranges 1 - 1.5 Hz ⇔ 3.5 - 4.5 Hz, which characterize the specific interactions of oscillations during the TA's burst activity. Using the Gabor transformation two measures of linear phase coupling, the phase-locking index (PLI) and the n:m phase synchronization index (PSI) have been determined. Phase-locking within the frequency ranges 1 -1.5 Hz and 3.5 - 4.5 Hz, and synchronization between both frequency ranges exists. These phase characteristics are significant 2 sec after burst onset and are associated with the maximum-values of the QPC(1 - 1.5 Hz ⇔ 3.5 - 4.5 Hz) which demonstrates that a specific neuronal coordination between the dynamics of phases and of amplitude-frequency dependencies must be underlying.
