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Related Experiment Video

Updated: Jun 6, 2026

Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver
08:25

Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver

Published on: August 27, 2021

An RF-powered wireless multi-channel implantable bio-sensing microsystem.

Darrin J Young1

  • 1University of Utah, Salt Lake City, Utah, USA. darrin.young@utah.edu

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
|November 25, 2010
PubMed
Summary

A novel wireless implantable biosensing microsystem monitors blood pressure, EKG, and body temperature in mice. This less-invasive system offers real-time physiological data for research animals.

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Related Experiment Videos

Last Updated: Jun 6, 2026

Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver
08:25

Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver

Published on: August 27, 2021

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa
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Published on: September 27, 2018

Area of Science:

  • Biomedical Engineering
  • Implantable Medical Devices
  • Wireless Biosensing

Background:

  • Conventional catheter-based sensors for physiological monitoring in laboratory animals pose risks like vessel occlusion and bleeding.
  • There is a need for less-invasive, untethered monitoring solutions for real-time physiological data acquisition in research settings.

Purpose of the Study:

  • To develop and characterize an RF-powered wireless implantable biosensing microsystem for simultaneous monitoring of blood pressure, electrocardiogram (EKG), and core body temperature in laboratory mice.
  • To introduce a novel, less-invasive blood pressure sensor utilizing a MEMS capacitive pressure sensor integrated into a silicone cuff.

Main Methods:

  • Development of a three-channel implantable microsystem powered wirelessly by an external RF source (4 MHz).
  • Integration of a flat silicone cuff with a MEMS capacitive pressure sensor for blood pressure measurement.
  • Characterization of the system's power consumption, sensing resolutions, and temperature sensitivity.

Main Results:

  • The microsystem achieves a blood pressure sensing resolution of 1 mmHg within a 1 kHz bandwidth.
  • EKG sensing resolution is 7.4 bits, and temperature sensitivity is 19 mV/°C across a 22 °C to 43 °C range.
  • The prototype sensor weighs 495 mg (approx. 2% of a mouse's body mass) and the system dissipates 200 microW.

Conclusions:

  • The developed wireless implantable biosensing microsystem provides a less-invasive and untethered solution for real-time physiological monitoring in laboratory mice.
  • The system's low power consumption, high sensing resolution, and minimal weight make it suitable for long-term animal studies.
  • Further in vivo validation in laboratory animals is ongoing to demonstrate the system's full potential.