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Updated: Jun 6, 2026

Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
Published on: October 17, 2016
Multimodal optical imaging for simultaneous in-vivo morphological and biochemical characterization of oral epithelial
Sebina Shrestha1, Jesung Park, Paritosh Pande
1Department of Biomedical Engineering at Texas A&M University, College Station, TX, USA.
Abstract:
Early detection of cancer is key to reducing morbidity and mortality. Morphological and chemical biomarkers presage the transition from normal to cancerous tissue. We have developed a noninvasive imaging system incorporating optical coherence tomography and fluorescence lifetime imaging to acquire both sets of biomarkers. Here we report early favorable results from an animal study designed to measure the capacity of this approach for early diagnosis of oral cancer.

