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Related Concept Videos

Modified-Release Drug Delivery Systems: Site-Targeted01:24

Modified-Release Drug Delivery Systems: Site-Targeted

Site-targeted drug delivery systems enhance therapeutic efficacy while minimizing systemic toxicity and treatment costs. Unlike conventional methods, these systems ensure precise drug delivery, improving bioavailability and reducing side effects. Targeted drug delivery is classified into three levels. First-order targeting directs drugs to the capillary beds of specific organs or tissues. Second-order targets specific cell types, such as tumor cells, using receptor-mediated interactions.
Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Modified-Release Drug Delivery Systems: Classification01:23

Modified-Release Drug Delivery Systems: Classification

Modified-release drug delivery systems improve drug efficacy and minimize side effects by controlling the rate and location of drug release. These systems fall into three categories: rate-programmed, stimuli-activated, and site-targeted.Rate-programmed systems release drugs at a predetermined rate, maintaining consistent therapeutic levels and reducing fluctuations that could lead to toxicity or subtherapeutic effects. These systems use polymeric matrices, reservoir-based designs, or osmotic...
Drug Delivery Systems: Different Types01:27

Drug Delivery Systems: Different Types

Conventional oral drug products, termed immediate-release (IR) formulations, are engineered to promptly release their active pharmaceutical ingredient (API) upon ingestion, typically in tablets or capsules. This rapid release often results in swift drug absorption and consequent pharmacodynamic effects, although the timing and intensity can vary depending on the drug's properties. Prodrugs within these formulations require metabolic conversion to activate their pharmacodynamic effects,...

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Related Experiment Video

Updated: Jun 6, 2026

Targeted Plasma Membrane Delivery of a Hydrophobic Cargo Encapsulated in a Liquid Crystal Nanoparticle Carrier
10:16

Targeted Plasma Membrane Delivery of a Hydrophobic Cargo Encapsulated in a Liquid Crystal Nanoparticle Carrier

Published on: February 8, 2017

Nanotechnology based targeted drug delivery.

Carmelina Ruggiero1, Laura Pastorino, Oscar L Herrera

  • 1Department of Communication, Computer and System Sciences, Nanobiotechnology and Medical Informatics Laboratory, University of Genova, Italy. carmel@dist.unige.it

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
|November 25, 2010
PubMed
Summary

Nanotechnology, specifically nanomedicine, offers targeted drug delivery solutions for therapeutics with poor pharmacokinetic properties. This approach enhances drug efficacy and safety by directing treatments to specific sites, minimizing off-target effects.

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Manufacture and Drug Delivery Applications of Silk Nanoparticles

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Area of Science:

  • Nanotechnology and Nanobiotechnology
  • Biotechnology and Medical Applications
  • Materials Science

Background:

  • Nanotechnology significantly impacts diverse industries including manufacturing, semiconductors, and biotechnology.
  • Nanobiotechnology integrates biological and synthetic materials at the molecular level for applications in biosensors, microchips, and medical treatments.
  • Nanomedicine leverages engineered nanodevices for disease diagnosis and treatment, with targeted drug delivery being a key focus.

Purpose of the Study:

  • To highlight the critical role of nanotechnology in advancing medical treatments and diagnostics.
  • To emphasize the importance of targeted drug delivery systems in overcoming the limitations of current therapeutics.
  • To explore various nanoscale systems developed for effective drug encapsulation and controlled release.

Main Methods:

  • Investigating the integration of biological and synthetic materials at the nanoscale.
  • Developing engineered nanodevices and nanostructures for medical applications.
  • Fabricating nanoparticles and nanocapsules for drug encapsulation and release.

Main Results:

  • Nanomedicine enables targeted drug delivery, improving therapeutic outcomes.
  • Nanoscale drug carriers can be engineered for specific release profiles.
  • Various nanoscale systems like liposomes, dendrimers, and nanoparticles show promise for drug delivery.

Conclusions:

  • Nanotechnology offers innovative solutions for drug delivery, addressing challenges in pharmacokinetics and biopharmaceutical properties.
  • Targeted drug delivery systems enhance drug efficacy and safety by minimizing side effects.
  • Continued research into nanocarriers is crucial for advancing nanomedicine and patient care.