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Oral Drug Delivery Systems: Continuous-Release Systems

Oral Drug Delivery Systems: Continuous-Release Systems

Continuous-release drug delivery systems offer a strategic approach to maintaining therapeutic drug levels over extended periods following oral administration. By modulating the release rate of active pharmaceutical ingredients, these systems minimize fluctuations in plasma concentrations, which enhances clinical efficacy and reduces the need for frequent dosing. Such characteristics make them particularly advantageous in managing chronic diseases where patient adherence and stable drug...

Modified-Release Drug Delivery Systems: Rate-Programmed I

Modified-Release Drug Delivery Systems: Rate-Programmed I

Rate-programmed drug delivery systems (DDS) are designed to release drugs at specific, controlled rates to maintain consistent therapeutic levels. These systems are categorized based on their release mechanisms, including dissolution-controlled DDS, diffusion-controlled DDS, and combined dissolution-diffusion-controlled DDS.In dissolution-controlled DDS, the release rate depends on the slow dissolution of the drug itself or the surrounding matrix. Drugs with inherently slow dissolution rates,...

Modified-Release Drug Delivery Systems: Classification

Modified-Release Drug Delivery Systems: Classification

Modified-release drug delivery systems improve drug efficacy and minimize side effects by controlling the rate and location of drug release. These systems fall into three categories: rate-programmed, stimuli-activated, and site-targeted.Rate-programmed systems release drugs at a predetermined rate, maintaining consistent therapeutic levels and reducing fluctuations that could lead to toxicity or subtherapeutic effects. These systems use polymeric matrices, reservoir-based designs, or osmotic...

Modified-Release Drug Delivery Systems: Rate-Programmed II

Modified-Release Drug Delivery Systems: Rate-Programmed II

Rate-programmed drug delivery systems release drugs in a controlled manner to maintain therapeutic levels. Three main designs include reservoir, matrix, and hybrid systems.Reservoir systems consist of a drug core enclosed within a membrane that controls drug release. In non-swelling reservoir systems, polymers like ethyl cellulose or polymethacrylates are used. These do not hydrate in aqueous media and control release through membrane thickness, porosity, or insolubility. This type includes...

Modified-Release Drug Delivery Systems: Stimuli-Activated

Modified-Release Drug Delivery Systems: Stimuli-Activated

Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also called...

Modified-Release Drug Delivery Systems: Site-Targeted

Modified-Release Drug Delivery Systems: Site-Targeted

Site-targeted drug delivery systems enhance therapeutic efficacy while minimizing systemic toxicity and treatment costs. Unlike conventional methods, these systems ensure precise drug delivery, improving bioavailability and reducing side effects. Targeted drug delivery is classified into three levels. First-order targeting directs drugs to the capillary beds of specific organs or tissues. Second-order targets specific cell types, such as tumor cells, using receptor-mediated interactions.

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Related Experiment Video

Updated: Jun 6, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

RMAIS: RFID-based medication Adherence Intelligence System.

Corey McCall¹, Branden Maynes, Cliff C Zou

¹School of Electrical Engineering and Computer Science, University of Central Florida, 4000 Central Florida Blvd., Orlando, FL 32816, USA.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

|November 25, 2010

Summary

This summary is machine-generated.

A new Radio-Frequency Identification (RFID)-based Medication Adherence Intelligence System (RMAIS) helps patients take medications correctly. This user-friendly system improves drug adherence for better health outcomes.

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Using a Real-Time Locating System to Measure Walking Activity Associated with Wandering Behaviors Among Institutionalized Older Adults

Published on: February 8, 2019

Area of Science:

Biomedical Engineering
Health Informatics
Patient Monitoring Systems

Background:

Poor medication adherence in outpatients, particularly the elderly, leads to adverse health consequences.
Current adherence monitoring technologies are often expensive or difficult for patients to use.

Purpose of the Study:

To design and prototype a marketable Radio-Frequency Identification (RFID)-based Medication Adherence Intelligence System (RMAIS).
To develop a user-friendly, patient-centered system for improving medication adherence in a home setting.

Main Methods:

Development of a novel motorized rotation platform integrated with a scale and RFID reader.
Implementation of an Internet-based notification system for patient reminders and physician alerts.
Design focused on automatic, fool-proof dispensing for multiple daily dosages.

Main Results:

A complete prototype of the RFID-based Medication Adherence Intelligence System (RMAIS) was successfully developed.
The system is designed for convenient use by ordinary patients in their homes.
The system facilitates timely medication intake and adherence monitoring.

Conclusions:

The RMAIS offers a practical and intelligent solution for improving medication adherence.
This technology can help patients maintain independence while managing complex medication schedules.
The system has the potential to reduce disease progression and improve patient quality of life.