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Updated: Jun 6, 2026

Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts
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Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts

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A CMOS-based multichip flexible retinal stimulator for simultaneous multi-site stimulation.

T Tokuda1, Y Sagawa, T Noda

  • 1Nara Institute Science and Technology, Takayama-cho 8916-5, Ikoma, 630-0192, JAPAN. tokuda@ms.naist.jp

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
|November 25, 2010
PubMed
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Researchers created a flexible neural stimulator for multi-site stimulation. This new device successfully demonstrated simultaneous retinal stimulation in a rabbit model.

Area of Science:

  • Biomedical Engineering
  • Neuroscience
  • Materials Science

Background:

  • Neural stimulation is crucial for treating neurological disorders.
  • Existing devices often lack multi-site stimulation capabilities.
  • Flexible electronics offer new possibilities for neural interfaces.

Purpose of the Study:

  • To develop a novel CMOS-based multichip flexible neural stimulator.
  • To enable simultaneous multi-site neural stimulation.
  • To propose and test a new multi-chip retinal stimulator design.

Main Methods:

  • Developed a novel CMOS-based multichip flexible neural stimulator with an on-chip stimulation generator.
  • Designed a new multi-chip retinal stimulator with a single electrode/unit chip configuration.

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Last Updated: Jun 6, 2026

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Published on: August 26, 2021

Methodology for Biomimetic Chemical Neuromodulation of Rat Retinas with the Neurotransmitter Glutamate In Vitro
12:56

Methodology for Biomimetic Chemical Neuromodulation of Rat Retinas with the Neurotransmitter Glutamate In Vitro

Published on: December 19, 2017

  • Performed in vivo retinal stimulation experiments in a rabbit model.

    • Main Results:

    • Achieved simultaneous multi-site stimulation.
    • Demonstrated the functionality of the novel multi-chip retinal stimulator.
    • Successfully conducted in vivo retinal stimulation experiments.

    Conclusions:

    • The developed neural stimulator enables simultaneous multi-site stimulation.
    • The novel multi-chip retinal stimulator design is effective.
    • This technology holds promise for advanced neural prosthetics.