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Updated: Jun 6, 2026

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance
Published on: May 2, 2018
[Transforming of the drug resistance plasmid from Staphylococcus aureus into Escherichia coli]
Wan-kelan Li1, Hong Jiang, Yong-fen Huang
1Medical College of Foshan University, Foshan 528000, China.
Objective:
To discuss the possible mechanism of drug resistance transmission between Staphylococcus and Escherichia coli.
Methods:
The chloramphenicol resistance plasmid of Staphylococcus aureus was extracted to transform the sensitive Escherichia coli, and the drug-resistant Escherichia coli were screened by drug sensitivity test.
Results:
The drug-resistant Escherichia coli were successfully obtained.
Conclusion:
Staphylococcus may have a natural shuttle plasmid of drug resistance, which can transform Escherichia coli under specific conditions.
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