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Published on: May 28, 2019
[Effect of plasmaslyte A on the liver function of patients undergoing cardiac surgery with extracorporeal
Bin-fei Li1, Xiao-li Xie, Zhi-gang Zhang
1Department of Anesthesiology, Zhongshan Affiliated Hospital of Sun Yat-sen University, Zhongshan 528403, China. lbf8@msn.com
Objective:
To observe the effect of plasmaslyte A on the liver function of patients receiving cardiac surgery with extracorporeal circulation.
Methods:
Sixty patients scheduled for cardiac surgery were randomized to receive plasmaslyte A (group P, n=30) and ringer lactate solution (group R, n=30). The two agents were used in priming heart-lung machine and intra- and postoperative crystal solution. All the patients were examined for the levels of AST, ALT and Lac the day before and at 2 h and 1, 3 and 7 days after the surgery. The time of extubation and length of stay at the ICU were record.
Results:
The levels of ALT, AST and Lac in group P were significantly lower than those in group R (P<0.05), and the duration of intubation and stay at the ICU was shorter in group P (P<0.05).
Conclusion:
Plasmaslyte A can markedly reduce the level of AST, ALT and Lac and protect the liver function of patients undergoing cardiac surgery with extracorporeal circulation.
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