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Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Endovascular interventions for acute pulmonary embolism.
Peter H Lin1, Huiting Chen, Carlos F Bechara
1Division of Vascular Surgery & Endovascular Therapy, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA. plin@bcm.edu
Perspectives in Vascular Surgery and Endovascular Therapy
|November 25, 2010
Summary
Massive pulmonary embolism (PE) is a life-threatening condition. This study analyzes endovascular treatments, including ultrasound-accelerated thrombolysis, for acute PE, offering insights into catheter-based interventions.
Area of Science:
- Cardiology
- Interventional Radiology
- Pulmonary Medicine
Background:
- Massive pulmonary embolism (PE) presents with hemodynamic instability and acute right ventricular (RV) failure, posing a high mortality risk.
- Submassive PE, characterized by RV failure or troponin elevation, can lead to severe outcomes without prompt intervention.
- Current management emphasizes rapid risk stratification and aggressive treatment for massive PE.
Purpose of the Study:
- To analyze various endovascular treatment strategies for massive and submassive pulmonary embolism (PE).
- To discuss institutional experience with ultrasound-accelerated and catheter-directed thrombolytic therapy for acute massive PE over a decade.
- To review clinical evidence supporting catheter-based interventions in PE management.
Main Methods:
- Analysis of diverse endovascular treatment strategies for PE.
- Review of a 10-year institutional experience with ultrasound-accelerated thrombolytic therapy (UATT) and catheter-directed thrombolysis (CDT) in acute massive PE.
- Examination of clinical evidence for catheter-based interventions in massive and submassive PE.
Main Results:
- Endovascular technologies offer various catheter-based thrombectomy and thrombolytic devices for PE treatment.
- Institutional data on UATT and CDT for acute massive PE over a 10-year period are presented.
- Clinical evidence regarding the efficacy of catheter-based interventions in massive and submassive PE is analyzed.
Conclusions:
- Endovascular therapies are increasingly utilized for managing massive and submassive PE.
- Catheter-based interventions, including UATT and CDT, represent viable therapeutic options for acute PE.
- Further analysis of clinical evidence supports the role of endovascular approaches in PE treatment paradigms.
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