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Intensive care admissions for children with imported malaria in the United kingdom

Mehdi Garbash1, Jonathan Round, Christopher J M Whitty

  • 1Paediatric Infectious Diseases Unit, St George's Hospital, London, United Kingdom.

The Pediatric Infectious Disease Journal
|November 25, 2010
PubMed

Insights

Severe pediatric malaria cases in England and Wales are rare but require intensive care. This study details 29 children with imported malaria needing intensive care, highlighting outcomes and management strategies for severe pediatric malaria.

Area of Science:

  • Pediatric Infectious Diseases
  • Tropical Medicine
  • Critical Care Medicine

Background:

  • Imported malaria in children presents a significant public health challenge in non-endemic regions.
  • Understanding the characteristics and outcomes of severe pediatric malaria is crucial for effective clinical management.

Purpose of the Study:

  • To describe the clinical features and outcomes of children with imported malaria admitted to intensive care units (ICUs).
  • To identify specific complications and management requirements in this vulnerable pediatric population.

Main Methods:

  • Retrospective analysis of 977 children diagnosed with imported malaria in England and Wales (2004-2008).
  • Focused review of 29 pediatric patients admitted to ICUs, detailing diagnoses, interventions, and outcomes.

Main Results:

  • Out of 977 children, 29 (3.0%) required ICU admission.
  • Key ICU admissions included cerebral malaria (10 cases), need for inotropes (4 cases), and concurrent septicemia (1 case).
  • Most ICU admissions were for monitoring (14 cases); no deaths occurred, but one child had cerebellar infarction.

Conclusions:

  • Pediatric imported malaria requiring intensive care is uncommon but associated with serious complications.
  • Prompt recognition and intensive care management are vital for favorable outcomes in severe pediatric malaria.
  • Cerebral malaria and the need for hemodynamic support are significant concerns in critically ill children with imported malaria.

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