Interaction of rumen development and renal gluconeogenesis in lambs

Renal gluconeogenesis of equal aged lambs with different states of rumen development was studied. Going from preruminantto ruminant stage, the rate of glucose formation from several precursors increased. Concomitantly urine pH shifted from acid to base state. Obviously, an enhanced secretion of H+ in lambs kidney during rumen development does not stimulate renal gluconeogenesis. Furthermore, there is no indication from our data that renal gluconeogenesis in lambs is inversely related to the activity of the sodium pump.