Mitomycin C-induced sister chromatid exchange in X chromosomes of Bovidae
L Iannuzzi1, G P Di Meo, A Perucatti
1Consiglio Nazionale delle Ricerche, Istituto di ricerche sull'Adattamento dei Bovini e dei Bufali all'Ambiente del Mezzogiorno, Naples, Italy.
Abstract:
Sister chromatid exchanges (SCEs) in early- and late-replicating X chromosomes of seven female cattle (Bos taurus L.) and five female river buffalo (Bubalus bubalis L.) were studied in untreated lymphocytes and lymphocytes treated with mitomycin C (MMC). In the experiment, 577 SCEs on X chromosomes of MMC-untreated cells and 825 SCEs on X chromosomes of MMC-treated cells from both species were observed. No significant differences between the number of SCEs in early- and late-replicating X chromosomes were found even when singular species and subjects were considered.
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