Related Experiment Videos
Psoriatic arthritis and myopathy
G T Thomson1, J L Johnston, F D Baragar
1Department of Medicine, University of Manitoba, Winnipeg, Canada.
The Journal of Rheumatology
|March 1, 1990
Summary
This study details a rare case of psoriatic myopathy, distinct from steroid-induced myopathy. New indicators like myalgia and elevated urine creatine may help track this condition.
Area of Science:
- Rheumatology
- Neurology
- Clinical Medicine
Background:
- Psoriatic arthritis is a chronic inflammatory disease.
- Myopathy can be associated with inflammatory conditions.
- Distinguishing between different types of myopathy is crucial for effective treatment.
Observation:
- A patient presented with psoriatic arthritis and concurrent myopathy.
- The myopathy's progression was independent of topical steroid use.
- No signs of hypercortisolism or localized steroid effects were observed.
Findings:
- The patient's condition was not consistent with polymyositis.
- Psoriatic myopathy is an infrequently documented condition.
- Myalgia and elevated 24-hour urine creatine levels were novel findings in psoriatic myopathy.
- Urine creatine elevation correlated with muscle weakness.
Implications:
- Psoriatic myopathy requires careful differentiation from steroid-induced myopathy.
- Myalgia and urine creatine levels may serve as valuable biomarkers for psoriatic myopathy.
- These findings contribute to understanding and managing this rare condition.