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Updated: Jun 6, 2026

Listeria monocytogenes Infection of the Brain
05:02

Listeria monocytogenes Infection of the Brain

Published on: October 2, 2018

Fulminant Endogenous Anterior Uveitis due to Listeria monocytogenes

Arno Hueber1, Gerhard Welsandt, Rafael S Grajewski

  • 1Centre of Ophthalmology, University Hospital of Cologne, Cologne, Germany.

Case Reports in Ophthalmology
|November 25, 2010
PubMed

Insights

A severe anterior uveitis case was diagnosed as Listeria monocytogenes infection. Prompt intravenous antibiotics successfully treated the infection, preserving vision and preventing endophthalmitis.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Endogenous uveitis can be sight-threatening.
  • Listeria monocytogenes is a rare cause of endogenous endophthalmitis.
  • Comorbidities and immunosuppression increase infection risk.

Observation:

  • A 67-year-old male with comorbidities presented with acute, severe anterior uveitis.
  • Listeria monocytogenes was identified via culture and PCR.

Findings:

  • Early, aggressive intravenous antibiotic treatment was initiated.
  • The patient's visual acuity was restored.
  • Endophthalmitis was averted, unlike in most reported cases.

Implications:

  • Prompt antimicrobial therapy is crucial for severe endogenous uveitis.
  • Systemic immunosuppression warrants vigilance for opportunistic infections.
  • Corticosteroid monotherapy for suspected bacterial uveitis should be avoided.

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