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Modeling Neonatal Intraventricular Hemorrhage Through Intraventricular Injection of Hemoglobin
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Published on: August 25, 2022

Brain herniation in a neonate.

C Y Wong1, A B Azizi, I Shareena

  • 1Department of Paediatrics, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Kuala Lumpur 56000, Malaysia. cheeyeng@gmail.com

Singapore Medical Journal
|November 25, 2010
PubMed
Summary
This summary is machine-generated.

Neonatal brain herniation from intracranial tumors is rare but possible. This case highlights the need for close monitoring of infants with brain tumors due to herniation risk.

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Area of Science:

  • Pediatric Neurosurgery
  • Neonatal Medicine
  • Oncology

Background:

  • Neonatal brain herniation is considered rare due to open fontanelles and sutures.
  • Literature review (1993-2008) found no reported cases of neonatal brain herniation secondary to intracranial tumors.

Observation:

  • A preterm infant with an antenatally diagnosed intracerebral tumor developed brain herniation.
  • Cerebral MRI revealed a large complex tumor causing significant mass effect and hydrocephalus.
  • The infant experienced tumor hemorrhage during attempted surgical excision.

Findings:

  • Histopathology confirmed an embryonal tumor, possibly an atypical rhabdoid/teratoid tumor.
  • The case demonstrates that neonatal intracranial tumors can lead to brain herniation.

Implications:

  • Intracranial tumors in newborns require vigilant monitoring for potential herniation.
  • This case challenges the assumption of rarity for neonatal brain herniation from tumors.
  • Early recognition and management strategies for neonatal brain tumors with herniation risk are crucial.