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Updated: Jun 6, 2026

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
Published on: August 14, 2013
[Panic after LASIK: acute medication-induced myopic recurrence after refractive surgery]
P S Muether1, G Welsandt, T S Dietlein
1Zentrum für Augenheilkunde, Universitätsklinik Köln, Kerpener Strasse 62, 50924 Köln, Deutschland. philmuether@mac.com
Abstract:
We report a case of acute myopic recurrence in a 38-year-old patient in a state of panic with a condition corresponding to LASIK 4 months earlier. The patient had commenced topiramate treatment 1 week previously, which is an antiepileptic drug also approved for migraine treatment. The symptoms were due to a rare topiramate-induced side effect (SE) with ciliochoroidal effusion, anterior shift of the lens-iris diaphragm and induced myopia. Cessation of topiramate led to complete remission of this idiosyncratic reaction, however, the patient's anxiety was impressive. Ocular administration of Topiramat-SE should thus be clarified.
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