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Updated: Jun 6, 2026

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
Published on: November 10, 2017
Lipid effects of endocrine medications
Dan V Mihailescu1, Avni Vora, Theodore Mazzone
1Department of Medicine, University of Illinois at Chicago, 1819 W. Polk Street, M/C 797, Chicago, IL, USA. danmih@uic.edu
Abstract:
Various alterations of lipid homeostasis have a significant role in the pathophysiology of the artherosclerotic process. The effects of usual lipid-lowering agents such as statins, fibrates, or niacin are well known, but other endocrine therapeutic agents could also affect the blood levels of various lipoproteins and, in turn, influence atheroma formation. In this review, we attempt to summarize the effect of several hormonal and non-hormonal endocrine agents on lipid metabolism, including insulin, thyroid hormone, sex hormones, glucocorticoids, growth hormone, and several anti-diabetic agents.
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