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Updated: Jun 6, 2026

Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
Women's perspective of botulinum toxin treatment for overactive bladder symptoms
G Alessandro Digesu1, Demetri Panayi, Caroline Hendricken
1Urogynaecology Department, Imperial College School of Medicine, St. Mary's Hospital, Cambridge Wing, Praed Street, London W2 1NY, UK. a.digesu@imperial.ac.uk
Introduction And Hypothesis:
This study aimed to evaluate the women's' views and expectations about outcomes and complications of botulinum toxin treatment for overactive bladder (OAB) symptoms.
Methods:
Consecutive women with OAB symptoms and detrusor overactivity were requested to fill out a multiple choice questionnaire to assess whether they would consider botulinum and what outcomes as well as complications they would find acceptable to undergo this treatment.
Results:
Two hundred sixty-one women, mean age of 58 (range, 38-78) years, were studied. Two hundred twenty-four were treatment-naive women (group A), while 37 were no responders to anticholinergics (group B). Only 49.6% of women in group A and 54% in group B would accept botulinum toxin. No significant differences were found between treatment-naive women and non-responders to anticholinergics (p > 0.05).
Conclusions:
Acceptance of botulinum toxin treatment involves a complex interaction of efficacy and possible complications. The balance of these factors changes the acceptability of the treatment.
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