Multimodality molecular imaging of the lung

Area of Science:

• Medical Imaging
• Pulmonology
• Radiology

Background:

• Chronic lung diseases continue to progress despite existing treatments.
• Molecular imaging is crucial for diagnosis, treatment planning, drug discovery, and therapy monitoring in lung diseases.
• Advancements in multimodality scanners like PET/CT, SPECT/CT, and MRI/PET enable sophisticated imaging biomarker probes.

Purpose of the Study:

• To review the potential applications of multimodality imaging in lung disease.
• To discuss established uses of molecular imaging in nononcologic lung pathophysiology and drug discovery.
• To highlight technical challenges in multimodality lung imaging.

Main Methods:

• Literature review of multimodality imaging techniques (PET/CT, SPECT/CT, MRI/PET).
• Analysis of molecular imaging applications in nononcologic lung conditions.
• Identification of technical challenges in lung imaging.

Main Results:

• Multimodality imaging offers enhanced capabilities for lung disease assessment.
• Molecular imaging is established in nononcologic lung pathophysiology and drug discovery.
• Technical challenges exist in implementing advanced multimodality imaging for the lung.

Conclusions:

• Multimodality molecular imaging holds significant potential for advancing the diagnosis and treatment of chronic lung diseases.
• Further research and technological development are needed to overcome existing challenges in lung imaging.