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Gender and hypertension management: a sub-analysis of the I-inSYST survey
Patricia Van der Niepen1, Dierik Verbeelen
1Department of Nephrology and Hypertension, Universitair Ziekenhuis Brussel, Brussels, Belgium. hemovnnp@uzbrussel.be
Insights
Blood pressure control is similar in men and women, though women have fewer cardiovascular risks. However, antihypertensive drug treatment differs by gender, with women receiving more diuretics.
Area of Science:
- Cardiology
- Hypertension Research
- Gender Health
Background:
- Hypertension is a primary risk factor for cardiovascular disease (CVD), the leading cause of death in women.
- Understanding gender-specific differences in hypertension management is crucial for effective CVD prevention.
Purpose of the Study:
- To compare blood pressure control, cardiovascular risk factors, organ damage, and treatment patterns between genders in hypertensive patients.
- To identify gender-based disparities in hypertension management within a primary care setting.
Main Methods:
- Analysis of data from 11,562 patients (49% women) in the cross-sectional I-inSyst survey.
- Evaluation of blood pressure control, prevalence of risk factors, organ damage, and prescribed antihypertensive medications stratified by gender.
Main Results:
- Similar blood pressure control rates were observed in women (21.8%) and men (21.2%), despite women being slightly older.
- Women exhibited fewer cardiovascular risk factors and organ damage, except for diabetes, cerebrovascular, and renal disease.
- Women received more antihypertensive drugs, predominantly diuretics, while men were more likely to receive calcium-channel blockers and ACE inhibitors.
Conclusions:
- Gender does not appear to be an independent factor influencing blood pressure control in treated hypertensive patients.
- Women generally present with a lower burden of cardiovascular risk factors and organ damage compared to men.
- Significant variations in antihypertensive medication prescribing exist between genders, warranting further investigation.
Abstract:
Hypertension is a major risk factor for cardiovascular disease, which is the leading cause of death in women. Aim. To evaluate blood pressure control, prevalence of concomitant cardiovascular risk factors, subclinical and clinical organ damage, and treatment according to gender. Methods. 11,562 patients (49% women) from the cross-sectional I-inSyst survey in primary care were included. Results. Blood pressure control in women (21.8%) and men (21.2%) was similar, despite a slightly older age (64.9 vs 63 years, p<0.0001). Women had less concomitant cardiovascular risk factors and organ damage, with the exception of diabetes, cerebrovascular and renal disease, than men. They received more antihypertensive drugs than men (1.7 ± 0.9 vs 1.5 ± 0.9, p<0.0001). Diuretics were more (45% vs 36.5%, p<0.0001), calcium-channel blockers (26% vs 29%, p<0.003) and angiotensin-converting enzyme inhibitors (20% vs 22%, p<0.02) were less commonly prescribed in women than in men. Different clinical factors (i.e. age, duration of hypertension, smoking) in women and men were associated with blood pressure control, but gender itself was not. Conclusions. In this group of treated hypertensive patients, blood pressure control in women and men was not different. Women had a lower prevalence of most cardiovascular risk factors, subclinical and clinical organ damage. Antihypertensive drug treatment varied according to gender.
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